Entry Detail



General Information

Database ID:SKCM07575
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PKMYT1
Full Name:protein kinase, membrane associated tyrosine/threonine 1
Category:mRNA
Synonyms:MYT1|PPP1R126
Chromosome:chr16
Strand:-
Coordinate:
Start Site(bp):2968024End Site(bp):2980539
Gene Summary:This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
External Links:
Ensembl ID:ENSG00000127564
HGNC ID:HGNC:29650
Entrez Gene:9088



Expression Profile of PKMYT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-150-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
YES
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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