ctcRbase

Entry Detail

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General Information

Database ID: SKCM07624 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BMP8B Full Name: bone morphogenetic protein 8b Category: mRNA Synonyms: BMP8|OP2 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 39757182 End Site(bp): 39788861 Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000116985 HGNC ID: HGNC:1075 Entrez Gene: 656

Expression Profile of BMP8B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-93-5p YES YES NO Display: