Entry Detail



General Information

Database ID:SKCM07686
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NXN
Full Name:nucleoredoxin
Category:mRNA
Synonyms:NRX|TRG-4
Chromosome:chr17
Strand:-
Coordinate:
Start Site(bp):799313End Site(bp):979770
Gene Summary:This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation. [provided by RefSeq, Sep 2015]
External Links:
Ensembl ID:ENSG00000167693
HGNC ID:HGNC:18008
Entrez Gene:64359



Expression Profile of NXN Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-140-3p
YES
NO
YES
hsa-miR-421
YES
YES
YES
hsa-miR-485-5p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-505-3p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
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