Entry Detail



General Information

Database ID:SKCM07689
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SETDB1
Full Name:SET domain bifurcated 1
Category:mRNA
Synonyms:ESET|H3-K9-HMTase4|KG1T|KMT1E|TDRD21
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):150926263End Site(bp):150964744
Gene Summary:This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
External Links:
Ensembl ID:ENSG00000143379
HGNC ID:HGNC:10761
Entrez Gene:9869



Expression Profile of SETDB1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-136-5p
YES
YES
NO
hsa-miR-28-5p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-29a-3p
YES
YES
YES
hsa-miR-29b-3p
YES
YES
YES
hsa-miR-29c-3p
YES
YES
YES
hsa-miR-300
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-708-5p
YES
YES
NO
hsa-miR-7-5p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
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