ctcRbase

Entry Detail

---



General Information

Database ID: SKCM07745 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SELENOI Full Name: selenoprotein I Category: mRNA Synonyms: EPT1|SELI|SEPI Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 26308547 End Site(bp): 26395891 Gene Summary: The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000138018 HGNC ID: HGNC:29361 Entrez Gene: 85465

Expression Profile of SELENOI Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES NO YES hsa-miR-1271-5p YES YES YES hsa-miR-1298-5p YES NO YES hsa-miR-143-3p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-182-5p YES YES NO hsa-miR-195-5p YES NO YES hsa-miR-197-3p YES NO NO hsa-miR-214-3p YES NO NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-217 YES YES YES hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-370-3p YES YES YES hsa-miR-424-5p YES NO YES hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-506-3p YES NO YES hsa-miR-520f-3p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES YES YES Display: