ctcRbase

Entry Detail

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General Information

Database ID: SKCM07746 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ABCC4 Full Name: ATP binding cassette subfamily C member 4 Category: mRNA Synonyms: MOAT-B|MOATB|MRP4 Chromosome: chr13 Strand: - Coordinate: Start Site(bp): 95019829 End Site(bp): 95301446 Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] External Links: Ensembl ID: ENSG00000125257 HGNC ID: HGNC:55 Entrez Gene: 10257

Expression Profile of ABCC4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-186-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-421 YES YES NO hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO Display: