ctcRbase

Entry Detail

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General Information

Database ID: SKCM07750 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TRIOBP Full Name: TRIO and F-actin binding protein Category: mRNA Synonyms: DFNB28|HRIHFB2122|TAP68|TARA|dJ37E16.4 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 37697004 End Site(bp): 37776556 Gene Summary: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008] External Links: Ensembl ID: ENSG00000100106 HGNC ID: HGNC:17009 Entrez Gene: 11078

Expression Profile of TRIOBP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-147a YES NO NO hsa-miR-17-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-210-3p YES YES NO hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-340-5p YES YES YES hsa-miR-423-5p YES NO YES hsa-miR-491-5p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES hsa-miR-98-5p YES YES YES Display: