ctcRbase

Entry Detail

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General Information

Database ID: SKCM07768 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LRIG2 Full Name: leucine rich repeats and immunoglobulin like domains 2 Category: mRNA Synonyms: LIG-2|LIG2|UFS2 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 113073209 End Site(bp): 113132260 Gene Summary: This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] External Links: Ensembl ID: ENSG00000198799 HGNC ID: HGNC:20889 Entrez Gene: 9860

Expression Profile of LRIG2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-192-5p YES NO YES hsa-miR-195-5p YES YES YES hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-215-5p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-424-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-98-5p YES YES YES Display: