ctcRbase

Entry Detail

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General Information

Database ID: SKCM07770 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SCRIB Full Name: scribbled planar cell polarity protein Category: mRNA Synonyms: CRIB1|SCRB1|SCRIB1|Vartul Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 143790920 End Site(bp): 143815379 Gene Summary: This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000180900 HGNC ID: HGNC:30377 Entrez Gene: 23513

Expression Profile of SCRIB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-9-5p YES YES YES hsa-miR-98-5p YES YES NO Display: