ctcRbase

Entry Detail

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General Information

Database ID: SKCM07776 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SORL1 Full Name: sortilin related receptor 1 Category: mRNA Synonyms: C11orf32|LR11|LRP9|SORLA|SorLA-1|gp250 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 121452203 End Site(bp): 121633693 Gene Summary: This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000137642 HGNC ID: HGNC:11185 Entrez Gene: 6653

Expression Profile of SORL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p NO YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-124-3p NO YES YES hsa-miR-128-3p NO YES YES hsa-miR-153-3p NO YES YES hsa-miR-17-5p YES YES YES hsa-miR-199a-5p NO YES YES hsa-miR-199b-5p NO YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-25-3p YES NO YES hsa-miR-27a-3p NO YES YES hsa-miR-27b-3p NO YES YES hsa-miR-32-5p YES NO YES hsa-miR-328-3p NO YES YES hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-431-5p NO YES YES hsa-miR-499a-5p NO YES YES hsa-miR-519d-3p YES YES YES hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES hsa-miR-93-5p YES YES YES Display: