Entry Detail



General Information

Database ID:SKCM07778
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FBXO9
Full Name:F-box protein 9
Category:mRNA
Synonyms:FBX9|NY-REN-57|VCIA1|dJ341E18.2
Chromosome:chr6
Strand:+
Coordinate:
Start Site(bp):53051991End Site(bp):53100873
Gene Summary:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000112146
HGNC ID:HGNC:13588
Entrez Gene:26268



Expression Profile of FBXO9 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-130a-3p
YES
YES
YES
hsa-miR-130b-3p
YES
YES
YES
hsa-miR-199a-5p
YES
NO
YES
hsa-miR-199b-5p
YES
NO
YES
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-218-5p
YES
YES
NO
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
YES
hsa-miR-301b-3p
YES
YES
YES
hsa-miR-329-3p
YES
NO
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-454-3p
YES
YES
YES
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