ctcRbase

Entry Detail

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General Information

Database ID: SKCM07780 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CDC42BPA Full Name: CDC42 binding protein kinase alpha Category: mRNA Synonyms: MRCK|MRCKA|PK428 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 226989865 End Site(bp): 227318474 Gene Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018] External Links: Ensembl ID: ENSG00000143776 HGNC ID: HGNC:1737 Entrez Gene: 8476

Expression Profile of CDC42BPA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES NO YES hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-137 YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-185-5p YES NO NO hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-214-3p YES NO NO hsa-miR-218-5p YES YES YES hsa-miR-25-3p YES NO YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-324-5p YES NO YES hsa-miR-32-5p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-340-5p YES NO YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-378a-3p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-422a YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-485-5p YES NO YES hsa-miR-653-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES hsa-miR-96-5p YES NO YES Display: