Entry Detail



General Information

Database ID:SKCM07800
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:THOP1
Full Name:thimet oligopeptidase 1
Category:mRNA
Synonyms:EP24.15|MEPD_HUMAN|MP78|TOP
Chromosome:chr19
Strand:+
Coordinate:
Start Site(bp):2785460End Site(bp):2815807
Gene Summary:The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]
External Links:
Ensembl ID:ENSG00000172009
HGNC ID:HGNC:11793
Entrez Gene:7064



Expression Profile of THOP1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
NO
YES
hsa-miR-130a-3p
YES
YES
YES
hsa-miR-130b-3p
YES
YES
YES
hsa-miR-301a-3p
YES
YES
YES
hsa-miR-301b-3p
YES
YES
YES
hsa-miR-454-3p
YES
YES
YES
hsa-miR-506-3p
YES
NO
YES
Display: