| ncRNA Symbol: | DYNC2H1 |
| Full Name: | dynein cytoplasmic 2 heavy chain 1 |
| Category: | mRNA |
| Synonyms: | ATD3|DHC1b|DHC2|DNCH2|DYH1B|SRPS2B|SRTD3|hdhc11 |
| Chromosome: | chr11 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 103109431 | End Site(bp): | 103479863 | |
| Gene Summary: | This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010] |
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