Entry Detail



General Information

Database ID:SKCM07926
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CPT1A
Full Name:carnitine palmitoyltransferase 1A
Category:mRNA
Synonyms:CPT1|CPT1-L|L-CPT1
Chromosome:chr11
Strand:-
Coordinate:
Start Site(bp):68754620End Site(bp):68844410
Gene Summary:The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000110090
HGNC ID:HGNC:2328
Entrez Gene:1374



Expression Profile of CPT1A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
NO
YES
YES
hsa-miR-148a-3p
NO
YES
YES
hsa-miR-148b-3p
NO
YES
YES
hsa-miR-152-3p
NO
YES
YES
hsa-miR-181a-5p
NO
YES
YES
hsa-miR-181b-5p
NO
YES
YES
hsa-miR-181c-5p
NO
YES
YES
hsa-miR-181d-5p
NO
YES
YES
hsa-miR-185-5p
YES
YES
NO
hsa-miR-188-5p
YES
NO
YES
hsa-miR-200b-3p
NO
YES
YES
hsa-miR-200c-3p
NO
YES
YES
hsa-miR-205-5p
YES
YES
NO
hsa-miR-324-5p
YES
YES
NO
hsa-miR-33a-5p
NO
YES
YES
hsa-miR-33b-5p
NO
YES
YES
hsa-miR-361-5p
YES
YES
NO
hsa-miR-365a-3p
YES
YES
YES
hsa-miR-429
NO
YES
YES
hsa-miR-494-3p
NO
YES
YES
Display: