Entry Detail



General Information

Database ID:SKCM07963
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FUK
Full Name:fucokinase
Category:mRNA
Synonyms:1110046B12Rik
Chromosome:chr16
Strand:+
Coordinate:
Start Site(bp):70454421End Site(bp):70480274
Gene Summary:The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000157353
HGNC ID:HGNC:29500
Entrez Gene:197258



Expression Profile of FUK Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A