ctcRbase

Entry Detail

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General Information

Database ID: SKCM07964 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MARK4 Full Name: microtubule affinity regulating kinase 4 Category: mRNA Synonyms: MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 45079288 End Site(bp): 45305283 Gene Summary: This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000007047 HGNC ID: HGNC:13538 Entrez Gene: 57787

Expression Profile of MARK4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-17-5p YES NO YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-423-5p YES NO YES hsa-miR-519d-3p YES NO YES hsa-miR-93-5p YES NO YES Display: