Entry Detail



General Information

Database ID:SKCM07975
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TP53BP2
Full Name:tumor protein p53 binding protein 2
Category:mRNA
Synonyms:53BP2|ASPP2|BBP|P53BP2|PPP1R13A
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):223779899End Site(bp):223845972
Gene Summary:This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000143514
HGNC ID:HGNC:12000
Entrez Gene:7159



Expression Profile of TP53BP2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
YES
hsa-miR-138-5p
YES
NO
YES
hsa-miR-142-5p
YES
NO
YES
hsa-miR-205-5p
YES
YES
YES
hsa-miR-212-3p
YES
YES
NO
hsa-miR-21-5p
YES
YES
NO
hsa-miR-219a-5p
YES
YES
YES
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-431-5p
YES
YES
NO
hsa-miR-590-5p
YES
YES
NO
hsa-miR-758-3p
YES
YES
NO
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