ctcRbase

Entry Detail

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General Information

Database ID: SKCM07977 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: STAM2 Full Name: signal transducing adaptor molecule 2 Category: mRNA Synonyms: Hbp|STAM2A|STAM2B Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 152116801 End Site(bp): 152175992 Gene Summary: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000115145 HGNC ID: HGNC:11358 Entrez Gene: 10254

Expression Profile of STAM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-5p YES YES NO hsa-miR-142-3p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-379-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-625-5p YES NO NO Display: