ctcRbase

Entry Detail

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General Information

Database ID: SKCM08031 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SNX13 Full Name: sorting nexin 13 Category: mRNA Synonyms: RGS-PX1 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 17790761 End Site(bp): 17940501 Gene Summary: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000071189 HGNC ID: HGNC:21335 Entrez Gene: 23161

Expression Profile of SNX13 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p NO YES YES hsa-miR-129-5p YES YES NO hsa-miR-1-3p NO YES YES hsa-miR-144-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-191-5p NO YES YES hsa-miR-204-5p YES YES NO hsa-miR-206 NO YES YES hsa-miR-211-5p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-24-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-376a-3p NO YES NO hsa-miR-376b-3p NO YES NO hsa-miR-377-3p YES YES NO hsa-miR-382-5p NO YES YES hsa-miR-410-3p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-613 NO YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: