ctcRbase

Entry Detail

---



General Information

Database ID: SKCM08033 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: OLR1 Full Name: oxidized low density lipoprotein receptor 1 Category: mRNA Synonyms: CLEC8A|LOX1|LOXIN|SCARE1|SLOX1 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 10158301 End Site(bp): 10172138 Gene Summary: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] External Links: Ensembl ID: ENSG00000173391 HGNC ID: HGNC:8133 Entrez Gene: 4973

Expression Profile of OLR1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-122-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-96-5p YES YES NO hsa-miR-98-5p YES NO YES Display: