Entry Detail



General Information

Database ID:SKCM08037
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NEK4
Full Name:NIMA related kinase 4
Category:mRNA
Synonyms:NRK2|STK2|pp12301
Chromosome:chr3
Strand:-
Coordinate:
Start Site(bp):52708449End Site(bp):52770949
Gene Summary:The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]
External Links:
Ensembl ID:ENSG00000114904
HGNC ID:HGNC:11399
Entrez Gene:6787



Expression Profile of NEK4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
NO
hsa-miR-1297
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-154-5p
YES
YES
NO
hsa-miR-218-5p
YES
YES
NO
hsa-miR-24-3p
YES
YES
YES
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-338-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-455-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-758-3p
YES
YES
NO
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