ctcRbase

Entry Detail

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General Information

Database ID: SKCM08043 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: KCTD1 Full Name: potassium channel tetramerization domain containing 1 Category: mRNA Synonyms: C18orf5 Chromosome: chr18 Strand: - Coordinate: Start Site(bp): 26454910 End Site(bp): 26657401 Gene Summary: This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome. [provided by RefSeq, May 2017] External Links: Ensembl ID: ENSG00000134504 HGNC ID: HGNC:18249 Entrez Gene: 284252

Expression Profile of KCTD1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES YES NO Display: