Entry Detail



General Information

Database ID:SKCM08051
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:STX5
Full Name:syntaxin 5
Category:mRNA
Synonyms:SED5|STX5A
Chromosome:chr11
Strand:-
Coordinate:
Start Site(bp):62806897End Site(bp):62832088
Gene Summary:This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
External Links:
Ensembl ID:ENSG00000162236
HGNC ID:HGNC:11440
Entrez Gene:6811



Expression Profile of STX5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-24-3p
YES
NO
YES
hsa-miR-34a-5p
YES
YES
NO
hsa-miR-34c-5p
YES
YES
NO
hsa-miR-449a
YES
YES
NO
hsa-miR-449b-5p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-7-5p
NO
YES
YES
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