ctcRbase

Entry Detail

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General Information

Database ID: SKCM08077 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: STEAP4 Full Name: STEAP4 metalloreductase Category: mRNA Synonyms: STAMP2|SchLAH|TIARP|TNFAIP9 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 88270892 End Site(bp): 88306891 Gene Summary: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011] External Links: Ensembl ID: ENSG00000127954 HGNC ID: HGNC:21923 Entrez Gene: 79689

Expression Profile of STEAP4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-488-3p YES YES NO Display: