ctcRbase

Entry Detail

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General Information

Database ID: SKCM08081 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SULF2 Full Name: sulfatase 2 Category: mRNA Synonyms: HSULF-2 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 47656348 End Site(bp): 47786616 Gene Summary: Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000196562 HGNC ID: HGNC:20392 Entrez Gene: 55959

Expression Profile of SULF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-138-5p YES YES YES hsa-miR-140-5p YES NO YES hsa-miR-141-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-370-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-98-5p YES NO YES Display: