ctcRbase

Entry Detail

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General Information

Database ID: SKCM08082 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LRRK2 Full Name: leucine rich repeat kinase 2 Category: mRNA Synonyms: AURA17|DARDARIN|PARK8|RIPK7|ROCO2 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 40196744 End Site(bp): 40369285 Gene Summary: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000188906 HGNC ID: HGNC:18618 Entrez Gene: 120892

Expression Profile of LRRK2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-454-3p YES YES NO Display: