ctcRbase

Entry Detail

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General Information

Database ID: SKCM08084 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LMNB2 Full Name: lamin B2 Category: mRNA Synonyms: EPM9|LAMB2|LMN2 Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 2427638 End Site(bp): 2456996 Gene Summary: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012] External Links: Ensembl ID: ENSG00000176619 HGNC ID: HGNC:6638 Entrez Gene: 84823

Expression Profile of LMNB2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES YES hsa-miR-1251-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-24-3p YES YES YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-34a-5p YES NO YES hsa-miR-34c-5p YES NO YES hsa-miR-449a YES NO YES hsa-miR-449b-5p YES NO YES hsa-miR-499a-5p YES YES YES hsa-miR-760 YES NO YES Display: