ctcRbase

Entry Detail

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General Information

Database ID: SKCM08101 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ACVRL1 Full Name: activin A receptor like type 1 Category: mRNA Synonyms: ACVRLK1|ALK-1|ALK1|HHT|HHT2|ORW2|SKR3|TSR-I Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 51906908 End Site(bp): 51923361 Gene Summary: This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000139567 HGNC ID: HGNC:175 Entrez Gene: 94

Expression Profile of ACVRL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-17-5p YES NO YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-214-3p YES YES NO hsa-miR-22-3p YES NO YES hsa-miR-324-3p YES NO NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES NO YES hsa-miR-34c-5p YES NO YES hsa-miR-365a-3p YES YES NO hsa-miR-449a YES NO YES hsa-miR-449b-5p YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-491-5p YES NO YES hsa-miR-519d-3p YES NO YES hsa-miR-532-3p YES NO YES hsa-miR-615-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-760 YES NO YES hsa-miR-93-5p YES NO YES Display: