Entry Detail



General Information

Database ID:SKCM08135
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TRIT1
Full Name:tRNA isopentenyltransferase 1
Category:mRNA
Synonyms:COXPD35|GRO1|IPPT|IPT|IPTase|MOD5|hGRO1
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):39841022End Site(bp):39883511
Gene Summary:This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]
External Links:
Ensembl ID:ENSG00000043514
HGNC ID:HGNC:20286
Entrez Gene:54802



Expression Profile of TRIT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
hsa-miR-28-5p
YES
YES
NO
hsa-miR-342-3p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-708-5p
YES
YES
NO
hsa-miR-9-5p
YES
YES
NO
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