ctcRbase

Entry Detail

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General Information

Database ID: SKCM08141 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NBL1 Full Name: NBL1, DAN family BMP antagonist Category: mRNA Synonyms: D1S1733E|DAN|DAND1|NB|NO3 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 19640554 End Site(bp): 19658456 Gene Summary: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000158747 HGNC ID: HGNC:7650 Entrez Gene: 4681

Expression Profile of NBL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-199a-5p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-324-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES Display: