Entry Detail



General Information

Database ID:SKCM08147
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:DOCK10
Full Name:dedicator of cytokinesis 10
Category:mRNA
Synonyms:DRIP2|Nbla10300|ZIZ3
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):224765090End Site(bp):225042445
Gene Summary:This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]
External Links:
Ensembl ID:ENSG00000135905
HGNC ID:HGNC:23479
Entrez Gene:55619



Expression Profile of DOCK10 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-141-3p
YES
YES
NO
hsa-miR-149-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-183-5p
YES
YES
NO
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-22-3p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-451a
YES
YES
NO
hsa-miR-455-5p
YES
YES
NO
hsa-miR-490-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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