Entry Detail



General Information

Database ID:SKCM08209
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FBXO3
Full Name:F-box protein 3
Category:mRNA
Synonyms:FBA|FBX3
Chromosome:chr11
Strand:-
Coordinate:
Start Site(bp):33740939End Site(bp):33774543
Gene Summary:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000110429
HGNC ID:HGNC:13582
Entrez Gene:26273



Expression Profile of FBXO3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1297
YES
YES
NO
hsa-miR-1298-5p
YES
NO
YES
hsa-miR-141-3p
YES
YES
NO
hsa-miR-142-3p
YES
YES
YES
hsa-miR-142-5p
YES
NO
YES
hsa-miR-143-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-219a-5p
YES
YES
YES
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-323a-3p
YES
NO
YES
hsa-miR-340-5p
YES
YES
YES
hsa-miR-362-5p
YES
NO
YES
hsa-miR-370-3p
YES
YES
YES
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
YES
hsa-miR-653-5p
YES
YES
NO
hsa-miR-668-3p
YES
NO
YES
hsa-miR-873-5p
YES
YES
YES
hsa-miR-876-5p
YES
YES
YES
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