ctcRbase

Entry Detail

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General Information

Database ID: SKCM08280 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DLG3 Full Name: discs large MAGUK scaffold protein 3 Category: mRNA Synonyms: MRX|MRX90|NEDLG|PPP1R82|SAP102|XLMR Chromosome: chrX Strand: + Coordinate: Start Site(bp): 70444861 End Site(bp): 70505490 Gene Summary: This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000082458 HGNC ID: HGNC:2902 Entrez Gene: 1741

Expression Profile of DLG3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-136-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-299-5p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-365a-3p YES NO YES hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES NO YES hsa-miR-374b-5p YES NO YES hsa-miR-375 YES NO YES hsa-miR-379-5p YES YES NO hsa-miR-410-3p YES NO YES hsa-miR-495-3p YES YES NO Display: