ctcRbase

Entry Detail

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General Information

Database ID: SKCM08285 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RRM2B Full Name: ribonucleotide reductase regulatory TP53 inducible subunit M2B Category: mRNA Synonyms: MTDPS8A|MTDPS8B|P53R2 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 102204502 End Site(bp): 102239118 Gene Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010] External Links: Ensembl ID: ENSG00000048392 HGNC ID: HGNC:17296 Entrez Gene: 50484

Expression Profile of RRM2B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-137 YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-142-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-216b-5p YES YES YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: