Entry Detail



General Information

Database ID:SKCM08304
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:LSS
Full Name:lanosterol synthase
Category:mRNA
Synonyms:CTRCT44|OSC
Chromosome:chr21
Strand:-
Coordinate:
Start Site(bp):46188141End Site(bp):46228824
Gene Summary:The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]
External Links:
Ensembl ID:ENSG00000160285
HGNC ID:HGNC:6708
Entrez Gene:4047



Expression Profile of LSS Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-10a-5p
YES
YES
NO
hsa-miR-10b-5p
YES
YES
NO
hsa-miR-139-5p
YES
YES
NO
hsa-miR-150-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-22-3p
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-451a
YES
YES
NO
hsa-miR-542-3p
YES
YES
NO
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