ctcRbase

Entry Detail

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General Information

Database ID: SKCM08308 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PTPN4 Full Name: protein tyrosine phosphatase, non-receptor type 4 Category: mRNA Synonyms: MEG|PTPMEG|PTPMEG1 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 119759631 End Site(bp): 119983818 Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000088179 HGNC ID: HGNC:9656 Entrez Gene: 5775

Expression Profile of PTPN4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES YES NO hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-129-5p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-183-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-302d-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-375 YES YES YES hsa-miR-424-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-93-5p YES YES YES Display: