ctcRbase

Entry Detail

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General Information

Database ID: SKCM08362 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: VAC14 Full Name: Vac14, PIKFYVE complex component Category: mRNA Synonyms: ArPIKfyve|TAX1BP2|TRX Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 70687439 End Site(bp): 70801161 Gene Summary: This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities. [provided by RefSeq, May 2017] External Links: Ensembl ID: ENSG00000103043 HGNC ID: HGNC:25507 Entrez Gene: 55697

Expression Profile of VAC14 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-381-3p YES YES NO Display: