ctcRbase

Entry Detail

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General Information

Database ID: SKCM08366 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: COQ2 Full Name: coenzyme Q2, polyprenyltransferase Category: mRNA Synonyms: CL640|COQ10D1|MSA1|PHB:PPT Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 83261536 End Site(bp): 83284914 Gene Summary: This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000173085 HGNC ID: HGNC:25223 Entrez Gene: 27235

Expression Profile of COQ2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES Display: