Entry Detail



General Information

Database ID:SKCM08374
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:STXBP5
Full Name:syntaxin binding protein 5
Category:mRNA
Synonyms:LGL3|LLGL3|Nbla04300
Chromosome:chr6
Strand:+
Coordinate:
Start Site(bp):147204425End Site(bp):147390476
Gene Summary:Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000164506
HGNC ID:HGNC:19665
Entrez Gene:134957



Expression Profile of STXBP5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
NO
YES
hsa-let-7b-5p
YES
NO
YES
hsa-let-7c-5p
YES
NO
YES
hsa-let-7d-5p
YES
NO
YES
hsa-let-7e-5p
YES
NO
YES
hsa-let-7f-5p
YES
NO
YES
hsa-let-7g-5p
YES
NO
YES
hsa-let-7i-5p
YES
NO
YES
hsa-miR-136-5p
YES
YES
NO
hsa-miR-138-5p
NO
YES
YES
hsa-miR-141-3p
YES
YES
YES
hsa-miR-143-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-148a-3p
YES
YES
NO
hsa-miR-148b-3p
YES
YES
NO
hsa-miR-152-3p
YES
YES
NO
hsa-miR-153-3p
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-197-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
YES
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-21-5p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-30a-5p
NO
YES
YES
hsa-miR-30b-5p
NO
YES
YES
hsa-miR-30c-5p
NO
YES
YES
hsa-miR-30d-5p
NO
YES
YES
hsa-miR-30e-5p
NO
YES
YES
hsa-miR-329-3p
YES
YES
NO
hsa-miR-338-3p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-590-5p
YES
YES
NO
hsa-miR-98-5p
YES
NO
YES
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