| ncRNA Symbol: | TPCN2 |
| Full Name: | two pore segment channel 2 |
| Category: | mRNA |
| Synonyms: | SHEP10|TPC2 |
| Chromosome: | chr11 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 69048897 | End Site(bp): | 69162440 |
|
| Gene Summary: | This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009] |
| External Links: | |