ctcRbase

Entry Detail

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General Information

Database ID: SKCM08381 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PKP2 Full Name: plakophilin 2 Category: mRNA Synonyms: ARVD9 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 32790745 End Site(bp): 32896840 Gene Summary: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000057294 HGNC ID: HGNC:9024 Entrez Gene: 5318

Expression Profile of PKP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-7-5p YES YES YES Display: