Entry Detail



General Information

Database ID:SKCM08393
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PDE10A
Full Name:phosphodiesterase 10A
Category:mRNA
Synonyms:ADSD2|HSPDE10A|IOLOD|LINC00473|PDE10A19
Chromosome:chr6
Strand:-
Coordinate:
Start Site(bp):165327287End Site(bp):165986603
Gene Summary:The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]
External Links:
Ensembl ID:ENSG00000112541
HGNC ID:HGNC:8772
Entrez Gene:10846



Expression Profile of PDE10A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
NO
YES
YES
hsa-miR-25-3p
NO
YES
YES
hsa-miR-27a-3p
NO
YES
YES
hsa-miR-27b-3p
NO
YES
YES
hsa-miR-32-5p
NO
YES
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-363-3p
NO
YES
YES
hsa-miR-367-3p
NO
YES
YES
hsa-miR-374a-5p
NO
YES
YES
hsa-miR-374b-5p
NO
YES
YES
hsa-miR-425-5p
YES
YES
NO
hsa-miR-448
NO
YES
YES
hsa-miR-92a-3p
NO
YES
YES
hsa-miR-92b-3p
NO
YES
YES
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