| ncRNA Symbol: | PHGDH |
| Full Name: | phosphoglycerate dehydrogenase |
| Category: | mRNA |
| Synonyms: | 3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA |
| Chromosome: | chr1 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 119648411 | End Site(bp): | 119744226 |
|
| Gene Summary: | This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011] |
| External Links: | |