Entry Detail



General Information

Database ID:SKCM08422
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:KLRG1
Full Name:killer cell lectin like receptor G1
Category:mRNA
Synonyms:2F1|CLEC15A|MAFA|MAFA-2F1|MAFA-L|MAFA-LIKE
Chromosome:chr12
Strand:+
Coordinate:
Start Site(bp):8950044End Site(bp):9010760
Gene Summary:Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]
External Links:
Ensembl ID:ENSG00000139187
HGNC ID:HGNC:6380
Entrez Gene:10219



Expression Profile of KLRG1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-365a-3p
YES
YES
NO
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