Entry Detail



General Information

Database ID:SKCM08426
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PI4KA
Full Name:phosphatidylinositol 4-kinase alpha
Category:mRNA
Synonyms:PI4K-ALPHA|PIK4CA|PMGYCHA|pi4K230
Chromosome:chr22
Strand:-
Coordinate:
Start Site(bp):20707691End Site(bp):20859417
Gene Summary:This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018]
External Links:
Ensembl ID:ENSG00000241973
HGNC ID:HGNC:8983
Entrez Gene:5297



Expression Profile of PI4KA Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-130a-3p
YES
YES
YES
hsa-miR-130b-3p
YES
YES
YES
hsa-miR-148a-3p
YES
YES
YES
hsa-miR-148b-3p
YES
YES
YES
hsa-miR-152-3p
YES
YES
YES
hsa-miR-153-3p
YES
YES
NO
hsa-miR-199a-5p
YES
NO
YES
hsa-miR-199b-5p
YES
NO
YES
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-219a-5p
YES
YES
YES
hsa-miR-29a-3p
YES
YES
NO
hsa-miR-29b-3p
YES
YES
NO
hsa-miR-29c-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
YES
hsa-miR-301b-3p
YES
YES
YES
hsa-miR-342-3p
YES
YES
NO
hsa-miR-454-3p
YES
YES
YES
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