ctcRbase

Entry Detail

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General Information

Database ID: SKCM08455 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ZNF346 Full Name: zinc finger protein 346 Category: mRNA Synonyms: JAZ|Zfp346 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 177022696 End Site(bp): 177081189 Gene Summary: The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015] External Links: Ensembl ID: ENSG00000113761 HGNC ID: HGNC:16403 Entrez Gene: 23567

Expression Profile of ZNF346 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-339-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-382-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-599 YES YES NO hsa-miR-873-5p YES YES NO Display: