ctcRbase

Entry Detail

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General Information

Database ID: SKCM08478 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MAPKAPK2 Full Name: mitogen-activated protein kinase-activated protein kinase 2 Category: mRNA Synonyms: MAPKAP-K2|MK-2|MK2 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 206684944 End Site(bp): 206734283 Gene Summary: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000162889 HGNC ID: HGNC:6887 Entrez Gene: 9261

Expression Profile of MAPKAPK2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-137 YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-224-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-296-3p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-335-5p YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-483-3p YES NO YES hsa-miR-486-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-9-5p YES YES YES Display: