ctcRbase

Entry Detail

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General Information

Database ID: SKCM08508 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NRF1 Full Name: nuclear respiratory factor 1 Category: mRNA Synonyms: ALPHA-PAL Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 129611714 End Site(bp): 129757082 Gene Summary: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014] External Links: Ensembl ID: ENSG00000106459 HGNC ID: HGNC:7996 Entrez Gene: 4899

Expression Profile of NRF1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-154-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-223-3p YES NO YES hsa-miR-25-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES YES YES hsa-miR-362-3p YES NO NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-371a-5p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-9-5p YES NO YES Display: