ctcRbase

Entry Detail

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General Information

Database ID: SKCM08537 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RNF217 Full Name: ring finger protein 217 Category: mRNA Synonyms: C6orf172|IBRDC1|OSTL|dJ84N20.1 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 124962545 End Site(bp): 125092633 Gene Summary: This protein encoded by this gene is a member of the RING1-IBR-RING24 (RBR) ubiquitin protein ligase family, and it belongs to a subfamily of these proteins that contain a transmembrane domain. This protein can interact with the HAX1 anti-apoptotic protein via its C-terminal RING finger motif, which suggests a role in apoptosis signaling. It is thought that deregulation of this gene can be a mechanism in leukemogenesis. Mutations in the region encoding the protein GXXXG motif, which appears to be necessary for protein self-association, have been found in human cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] External Links: Ensembl ID: ENSG00000146373 HGNC ID: HGNC:21487 Entrez Gene: 154214

Expression Profile of RNF217 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-211-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES NO Display: